Survivors of Childhood Heart Defects may have higher risk of Premature Dementia
March 6, 2018
Circulation Journal Report
Dallas, TX – People born with heart defects who survive into adulthood may be at higher risk of developing dementia, particularly dementia that starts before 65 years of age, according to new research in the American Heart Association’s journal Circulation.
With improved newborn and childhood treatments, more people born with heart defects survive into adulthood. A 2016 study published in Circulation estimated that approximately 1.4 million adults are living with congenital heart defects in the United States.

Children born with heart defects are more likely to survive into old age because of improved early treatments, but they may be more likely to develop early-onset dementia than people born without heart defects. (American Heart Association)
Top Heart Disease and Stroke Research advances of 2017
March 5, 2018
Dallas, TX – New medicines to fight heart disease, updated guidelines for strokes and high blood pressure, and research into genome editing are among the top heart disease and stroke advances in 2017, according to the American Heart Association, the world’s leading voluntary health organization devoted to fighting cardiovascular disease and stroke.
The Association, one of the top funders of heart- and stroke-related research worldwide, has been compiling an annual top 10 list of major advances in heart disease and stroke science since 1996. Here, in no particular order, are the organization’s picks for leading research accomplishments published in 2017.

American Heart Association identifies most impactful scientific discoveries for Heart Disease and Stroke. (American Heart Association)
American Heart Association reports Breast Cancer Treatments may increase the risk of Heart Disease
March 3, 2018
Dallas, TX – Breast cancer patients may be at an increased risk of cardiovascular diseases including heart failure and may benefit from a treatment approach that weighs the benefits of specific therapies against potential damage to the heart, according to a new scientific statement from the American Heart Association published in its journal Circulation.
The statement is an overview of what we currently know about risk factors common to both heart disease and breast cancer, the potential heart damage from some breast cancer treatments, and suggested strategies to prevent or minimize the damage.

Breast cancer survivors, especially older women, are more likely to die from cardiovascular diseases such as heart failure rather than breast cancer. (American Heart Association)
Guideline Adherence, not Patient Volume, may be better Hospital Heart Failure Metric
February 26, 2018
Circulation Journal Report
Dallas, TX – In evaluating the quality of care given to those hospitalized with heart failure, adherence to clinical guidelines may be a better measure of quality than the number of heart failure patients a hospital admits, according to new research in the American Heart Association’s journal Circulation.
Patients with heart failure are unable to pump enough blood and oxygen to their bodies to remain healthy. According to the American Heart Association’s 2017 Heart Disease and Stroke Statistical Update, 6.5 million Americans suffer from this chronic condition—and that number is growing.
Middle-Aged Couch Potatoes may reverse Heart Effects of a Sedentary Life with Exercise Training
January 10, 2018
Circulation Journal Report
Dallas, TX – Middle-aged couch potatoes may reduce or reverse the risk of heart failure associated with years of sitting if they participate in two years of regular aerobic exercise training, according to a new study in the American Heart Association’s journal Circulation.
Study participants who adhered to the aerobic exercise regimen had significant improvements in how their body used oxygen and had decreased cardiac stiffness after two years, both markers of a healthier heart.

Two years of exercise training during middle age may reduce or reverse the cardiac consequences of a sedentary lifestyle.
Abuse and adversity in childhood linked to more cardiovascular risk in adulthood
December 19, 2017
American Heart Association Scientific Statement
Dallas, TX – Children and teens who are abused, witness violence, are bullied or face other adversities are more likely to develop cardiovascular diseases in adulthood, according to a new scientific statement by the American Heart Association published in the Association’s journal Circulation.
The statement is based on a review of existing scientific research published in peer-reviewed medical journals that documents a strong association between adverse experiences in childhood and teen years and a greater likelihood of developing risk factors such as obesity, high blood pressure and type 2 diabetes earlier than those not experiencing adverse experiences.

Children and teens who experience abuse, bullying, neglect or witness violence and other forms of adversity are more likely to develop heart and blood vessel diseases as adults. (American Heart Association)
More physical activity and higher intensity physical activity may significantly reduce risk of death in older women in the short term
November 8, 2017
Circulation Journal Report
Dallas, TX – More physical activity and at higher intensities could lead to a big drop in the risk of death in older women from any cause, according to new research in the American Heart Association’s journal Circulation.
Researchers found the volume of light intensity physical activity or sedentary behavior was not associated with death rate. However, light intensity activity may be beneficial for other health outcomes not studied in this research.

Moderate to vigorous exercise, like brisk walking, cut the risk of death up to 70 percent among older women. Source: Circulation, November 6th, 2017, Accelerometer-Measured Physical Activity and Sedentary Behavior in Relation to All-Cause Mortality. (American Heart Association)
American Heart Association says Less than half of Patients prescribed new Cholesterol Drug receive Insurance Approval
November 3, 2017
Circulation Journal Report
Dallas, TX – Less than half of patients received their insurer’s approval for prescriptions of PCSK9 inhibitors, according to new research in the American Heart Association’s journal Circulation.
PCSK9 inhibitors, like Repatha (evolocumab) and Praluent (alirocumab), work by increasing the removal of low-density lipoprotein (LDL) or “bad” cholesterol from the blood. They have been shown to reduce LDL by 60 percent and decrease major cardiac events but cost much more than other cholesterol-lowering drugs with an average cost of $14,300 per year. Prescriptions require prior authorization by health insurance companies.
Men develop Irregular Heartbeat earlier than Women
October 19, 2017
Circulation Journal Report
Dallas, TX – Men develop a type of irregular heartbeat, known as atrial fibrillation, about a decade earlier than women on average, and being overweight is a major risk factor, according to a large new study published in the American Heart Association’s journal Circulation.
In atrial fibrillation, the upper chambers of the heart, or atria, quiver instead of beat to move blood effectively.

The risk of developing the irregular rhythm known as atrial fibrillation rises with increasing age and weight.
American Heart Association reports Scientists think Public Opinion important before Human Gene Editing
October 8, 2017
Circulation: Cardiovascular Genetics Journal Report
Dallas, TX – The public should be consulted before gene editing is used to treat human embryos, according to a survey of scientists published in the American Heart Association’s journal Circulation: Cardiovascular Genetics.
“Early studies with human embryos have established the feasibility of human germline genome editing but raise complex social, ethical and legal questions,” said Kiran Musunuru, M.D., Ph.D., MPH, lead survey author and an associate professor of cardiovascular medicine and genetics at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia.










