![\"American](\"http:\/\/www.clarksvilleonline.com\/wp-content\/uploads\/2010\/12\/American-Heart-Association-new-logo-480x230.jpg\" "\\"American"){kind=logo}
Houston, TX<\/strong> – People who have heart disease risks<\/a> in middle age \u2013 such as diabetes, high blood pressure or smoking \u2013 are at higher risk for dementia<\/a> later in life, according to research presented at the American Stroke Association\u2019s International Stroke Conference 2017.<\/p>\n\u201cThe health of your vascular system in midlife is really important to the health of your brain when you are older,\u201d said Rebecca F. Gottesman, M.D., Ph.D., lead researcher and associate professor of neurology and epidemiology at the Johns Hopkins University in Baltimore.<\/p>\n
![\"Cardiovascular](\"http:\/\/www.clarksvilleonline.com\/wp-content\/uploads\/2017\/03\/Dementia-Information-Graphic-480x240.jpg\" "\\"Cardiovascular")
<\/a>Cardiovascular disease risk factors in midle age increase dementia risk later in life. Dementia was: 41% higher in smokers; 39% higher in people with high blood pressure; 77% higher in people with diabetes. (American Heart Association)<\/p><\/div>\n
<\/p>\n
In an ongoing study that began in 1987 and enrolled 15,744 people in four U.S. communities, the risk of dementia increased as people got older.<\/p>\n
That was no surprise, but heart disease risks detected at the start of the study, when participants were between 45-64 years of age, also had a significant impact on later dementia, researchers noted.<\/p>\n
Dementia developed in 1,516 people during the study, and the researchers found that the risk of dementia later in life was:<\/h4>\n\n- 41 percent higher in midlife smokers than in non-smokers or former smokers;<\/li>\n
- 39 percent higher in people with high blood pressure (\u2265140\/90 mmHg) in middle age, and 31 percent higher in those with pre-hypertension (between 120\/80 mmHg and 139\/89 mmHg) compared to those with normal blood pressure; and<\/li>\n
- 77 percent higher in people with diabetes in middle age than in non-diabetics.<\/li>\n<\/ul>\n
\u201cDiabetes raises the risk almost as much as the most important known genetic risk factor for Alzheimer\u2019s disease,\u201d Gottesman said.<\/p>\n
Overall, the risk of dementia was 11 percent lower in women. The risk was highest in individuals who were black, had less than a high school education, were older, carried the gene known to increase Alzheimer\u2019s risk, or had high blood pressure, diabetes or were current smokers at the time of initial evaluation.<\/p>\n
Smoking and carrying the gene known to increase the chance of Alzheimer\u2019s were stronger risk factors in whites than in blacks, the researchers noted.<\/p>\n
\u201cIf you knew you carried the gene increasing Alzheimer\u2019s risk, you would know you were predisposed to dementia, but people don\u2019t necessarily think of heart disease risks in the same way. If you want to protect your brain as you get older, stop smoking, watch your weight, and go to the doctor so diabetes and high blood pressure can be detected and treated,\u201d said Gottesman.<\/p>\n
Because Atherosclerosis Risk in Communities is an observational study, the current study could not test whether treating heart risk factors will result in a lessened dementia risk later in life.<\/p>\n
\u201cThe benefit is that this is a long-term study and we know a lot about these people. Data like these may supplement data from clinical trials that look at the impact of treatment for heart disease risks,\u201d Gottesman said.<\/p>\n
Co-authors include Marilyn Albert, Ph.D.; Alvaro Alonso, M.D., Ph.D.; Laura H. Coker, Ph.D.; Josef Coresh, M.D., Ph.D.; Sonia M. Davis, Dr.P.H.; Jennifer A. Deal, Ph.D.; Guy M. McKhann, M.D.; Thomas H. Mosley, Ph.D.; A. Richey Sharrett, M.D., Dr.P.H.; Andrea L.C. Schneider, M.D., Ph.D.; B. Gwen Windham, M.D., M.H.S.; Lisa M. Wruck, Ph.D. and David S. Knopman, M.D.<\/p>\n
Author disclosures are on the abstract.<\/p>\n
The study was funded by the National Heart, Lung and Blood Institute and the National Institute of Neurological Disorders and Stroke.<\/p>\n
Additional Resources<\/strong><\/p>\n\n- See additional information on how to protect your heart\/protect your brain<\/a>.<\/u><\/li>\n
- Follow news from ASA International Stroke Conference 2017 via Twitter @HeartNews<\/a> #ISC17.<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"
American Stroke Association Meeting Report Houston, TX – People who have heart disease risks in middle age \u2013 such as diabetes, high blood pressure or smoking \u2013 are at higher risk for dementia later in life, according to research presented at the American Stroke Association\u2019s International Stroke Conference 2017. \u201cThe health of your vascular system […]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[86],"tags":[11530,7102,2538,2975,7304,9207,7101,216,218,215,5023,2558,11529,941],"class_list":["post-12382","post","type-post","status-publish","format-standard","hentry","category-health","tag-alzheimer","tag-alzheimers-disease","tag-american-heart-association","tag-american-stroke-association","tag-atherosclerosis","tag-baltimore-md","tag-dementia","tag-diabetes","tag-heart-disease","tag-high-blood-pressure","tag-houston-tx","tag-hypertension","tag-john-hopkins-university","tag-smoking"],"_links":{"self":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/comments?post=12382"}],"version-history":[{"count":1,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382\/revisions"}],"predecessor-version":[{"id":12383,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382\/revisions\/12383"}],"wp:attachment":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/media?parent=12382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/categories?post=12382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/tags?post=12382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u201cDiabetes raises the risk almost as much as the most important known genetic risk factor for Alzheimer\u2019s disease,\u201d Gottesman said.<\/p>\n
Overall, the risk of dementia was 11 percent lower in women. The risk was highest in individuals who were black, had less than a high school education, were older, carried the gene known to increase Alzheimer\u2019s risk, or had high blood pressure, diabetes or were current smokers at the time of initial evaluation.<\/p>\n
Smoking and carrying the gene known to increase the chance of Alzheimer\u2019s were stronger risk factors in whites than in blacks, the researchers noted.<\/p>\n
\u201cIf you knew you carried the gene increasing Alzheimer\u2019s risk, you would know you were predisposed to dementia, but people don\u2019t necessarily think of heart disease risks in the same way. If you want to protect your brain as you get older, stop smoking, watch your weight, and go to the doctor so diabetes and high blood pressure can be detected and treated,\u201d said Gottesman.<\/p>\n
Because Atherosclerosis Risk in Communities is an observational study, the current study could not test whether treating heart risk factors will result in a lessened dementia risk later in life.<\/p>\n
\u201cThe benefit is that this is a long-term study and we know a lot about these people. Data like these may supplement data from clinical trials that look at the impact of treatment for heart disease risks,\u201d Gottesman said.<\/p>\n
Co-authors include Marilyn Albert, Ph.D.; Alvaro Alonso, M.D., Ph.D.; Laura H. Coker, Ph.D.; Josef Coresh, M.D., Ph.D.; Sonia M. Davis, Dr.P.H.; Jennifer A. Deal, Ph.D.; Guy M. McKhann, M.D.; Thomas H. Mosley, Ph.D.; A. Richey Sharrett, M.D., Dr.P.H.; Andrea L.C. Schneider, M.D., Ph.D.; B. Gwen Windham, M.D., M.H.S.; Lisa M. Wruck, Ph.D. and David S. Knopman, M.D.<\/p>\n
Author disclosures are on the abstract.<\/p>\n
The study was funded by the National Heart, Lung and Blood Institute and the National Institute of Neurological Disorders and Stroke.<\/p>\n
Additional Resources<\/strong><\/p>\n American Stroke Association Meeting Report Houston, TX – People who have heart disease risks in middle age \u2013 such as diabetes, high blood pressure or smoking \u2013 are at higher risk for dementia later in life, according to research presented at the American Stroke Association\u2019s International Stroke Conference 2017. \u201cThe health of your vascular system […]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[86],"tags":[11530,7102,2538,2975,7304,9207,7101,216,218,215,5023,2558,11529,941],"class_list":["post-12382","post","type-post","status-publish","format-standard","hentry","category-health","tag-alzheimer","tag-alzheimers-disease","tag-american-heart-association","tag-american-stroke-association","tag-atherosclerosis","tag-baltimore-md","tag-dementia","tag-diabetes","tag-heart-disease","tag-high-blood-pressure","tag-houston-tx","tag-hypertension","tag-john-hopkins-university","tag-smoking"],"_links":{"self":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/comments?post=12382"}],"version-history":[{"count":1,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382\/revisions"}],"predecessor-version":[{"id":12383,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/posts\/12382\/revisions\/12383"}],"wp:attachment":[{"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/media?parent=12382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/categories?post=12382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.paristn.net\/articles\/wp-json\/wp\/v2\/tags?post=12382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\n