{"id":11472,"date":"2016-07-02T08:00:33","date_gmt":"2016-07-02T13:00:33","guid":{"rendered":"http:\/\/www.paristn.net\/articles\/?p=11472"},"modified":"2016-07-01T16:45:40","modified_gmt":"2016-07-01T21:45:40","slug":"american-heart-association-says-genetically-inherited-high-cholesterol-increases-long-term-risks-of-coronary-heart-disease-and-stroke","status":"publish","type":"post","link":"https:\/\/www.paristn.net\/articles\/2016\/07\/02\/american-heart-association-says-genetically-inherited-high-cholesterol-increases-long-term-risks-of-coronary-heart-disease-and-stroke\/","title":{"rendered":"American Heart Association says Genetically inherited High Cholesterol increases long-term risks of Coronary Heart Disease and Stroke"},"content":{"rendered":"

American Heart Association Rapid Access Journal Report<\/h2>\n

\"AmericanDallas, TX<\/strong> – Patients who experience high cholesterol due to an inherited genetic disorder from one of their parents\u2014heterozygous familial hypercholesterolemia\u2014 are much more likely than those with average cholesterol levels to have diseases caused by hardening of the arteries<\/a>, including an accelerated onset of coronary heart disease<\/a> by up to 30 years, according to new research in the American Heart Association journal Circulation<\/em>.<\/p>\n

The inherited form of high cholesterol\u2014familial hypercholesterolemia\u2014is a genetic disorder that is passed down through families.<\/p>\n

\"Prepping<\/a>

Prepping the patient to draw blood for a cholesterol test. (American Heart Association)<\/p><\/div>\n

Individuals with familial hypercholesterolemia have a genetic mutation that prevents the liver from removing excess low-density lipoprotein (LDL), known as \u201cbad\u201d cholesterol<\/a>, from their blood.<\/p>\n

Familial hypercholesterolemia is suspected when an individual has an LDL cholesterol level greater or equal to 190 mg\/dL (which was considered the familial hypercholesterolemia \u201cphenotype\u201d in this paper) in the setting of a family history of premature cardiovascular events.<\/p>\n

Researchers estimate that heterozygous familial hypercholesterolemia affects up to about 1.5 million people in the United States.<\/p>\n

Using pooled data from six groups of people in epidemiological studies (with 1.2 million person-years of follow-up), researchers found that patients with the familial hypercholesterolemia phenotype were:<\/p>\n