Yellow Pages -  Business Directory Plus
Detailed Weather Reports, Event Calendar and Movie Showtimes
Home - Set as Homepage - Add to Favorites - Contact Us
Discover Paris TN,  Henry County Tennessee
Discover Paris TN,  Henry County Tennessee Photo Gallery and Video Gallery
Detailed Weather Reports, Event Calendar and Movie Showtimes Wednesday - August 23, 2017  
Yellow Pages -  Business Directory Plus


 
Information Articles for the Paris TN and Henry County Tennessee area

Articles

Information Articles for the Paris TN and Henry County Tennessee area

American Heart Association says “Bad” air may impact “Good” Cholesterol increasing Heart Disease Risk

April 16, 2017 | Email This Post Print This Post
 

Arteriosclerosis, Thrombosis, and Vascular Biology Journal Report

American Heart AssociationDallas, TX – Traffic-related air pollution may increase cardiovascular disease risk by lowering levels of high-density lipoprotein (HDL), commonly known as “good” cholesterol, according to new research in the American Heart Association’s journal Arteriosclerosis, Thrombosis, and Vascular Biology.

Scientists have long known that air pollution increases the risk of developing cardiovascular diseases including atherosclerosis and heart failure, but are uncertain how the two are connected.

(At left), Air quality equipment monitors traffic-related air pollution on a New York City highway. (The MESA Air Study)

(At left), Air quality equipment monitors traffic-related air pollution on a New York City highway. (The MESA Air Study)

The connection may be explained by a reduction in the number of small, cholesterol-depleted HDL particles, leaving the average amount of cholesterol in HDL particles higher on a per-particle basis.

Recent evidence suggests that the number and functionality of HDL particles may be a better gauge of HDL’s heart-healthy effects than their cholesterol content, said lead author Griffith Bell, Ph.D., M.P.H., from the University of Washington School of Public Health in Seattle.

In a study of 6,654 middle-aged and older U.S. adults from diverse ethnic backgrounds, participants living in areas with high levels of traffic-related air pollution tended to have lower HDL levels.

Researchers found:

  • Higher exposure to black carbon (a marker of traffic-related pollution) averaged over a one year period was significantly associated with a lower “good” cholesterol level.
  • Higher particulate matter exposure over three months was associated with a lower HDL particle number.
  • Men and women responded to air pollutants differently: HDL was lower at higher pollution exposure for both sexes, but the magnitude was greater in women.

The lower levels of HDL observed with high levels of air pollution “may put individuals at a higher risk for cardiovascular disease down the line,” Bell said.

Changes in HDL levels may already appear after brief and medium-length exposures to air pollution, the authors noted.

The findings are part of the Multi-Ethnic Study of Atherosclerosis, an ongoing U.S. study examining the lifestyle factors that predict development of cardiovascular disease. This study follows a large, diverse population and unlike many previous studies on the health effects of air pollution that assumed individuals living in the same city have the same level of air pollution exposure, this study used cohort-focused monitoring campaigns looking at time and place to estimate air pollution exposure for each study participant, Bell said. It is also the first large cohort study to examine associations between air pollution and HDL particle number, he added.

However, HDL particle numbers were measured only once in this analysis, so “we were unable to examine whether they changed over time,” Bell noted. Continuing to track how HDL levels change with extent of exposure to traffic air pollution and investigating how air pollution interferes with HDL’s activity in the body will help confirm and understand the role of HDL, Bell added. Nonetheless, “our study helps strengthen the biological plausibility of the link between traffic-related air pollution and cardiovascular disease,” he said. “We’re slowly beginning to understand some of the biology of how that link works.”  

Co-authors are Samia Mora, M.D.; Philip Greenland, M.D.; Michael Tsai, Ph.D.; Edward A. Gill, M.D. and Joel D. Kaufman, M.D., M.P.H. Author disclosures are on the manuscript.

The National Heart, Lung, and Blood Institute, National Center for Research Resources, National Institute for Environmental Health Sciences, U.S. Environmental Protection Agency, and LipoScience, Inc. funded this study.

Additional Resources

Be Sociable, Share!
 

Comments

Feel free to leave a comment...
and oh, if you want a pic to show with your comment, go get a gravatar!

You must be logged in to post a comment.

 
|Home|Articles|Movie Theatre|Photo Gallery|Weather|Contact Us|
 
 
©2008 Discover Paris TN, Paris TN Web Design and Hosting by Compu-Net Enterprises.